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The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus

The sperm head-to-tail coupling apparatus (HTCA) ensures sperm head-tail integrity while defective HTCA causes acephalic spermatozoa, rendering males infertile. Here, we show that CENTLEIN is indispensable for HTCA integrity and function, and that inactivation of CENTLEIN in mice leads to sperm deca...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Liu, Chao, Wu, Bingbing, Li, Liansheng, Li, Wei, Yuan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363609/
https://www.ncbi.nlm.nih.gov/pubmed/34389728
http://dx.doi.org/10.1038/s41467-021-25227-w