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SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns

Human pre-mRNA introns vary in size from under fifty to over a million nucleotides. We searched for essential factors involved in the splicing of human short introns by screening siRNAs against 154 human nuclear proteins. The splicing activity was assayed with a model HNRNPH1 pre-mRNA containing sho...

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Detalles Bibliográficos
Autores principales: Fukumura, Kazuhiro, Yoshimoto, Rei, Sperotto, Luca, Kang, Hyun-Seo, Hirose, Tetsuro, Inoue, Kunio, Sattler, Michael, Mayeda, Akila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363638/
https://www.ncbi.nlm.nih.gov/pubmed/34389706
http://dx.doi.org/10.1038/s41467-021-24879-y