Facile access to C-glycosyl amino acids and peptides via Ni-catalyzed reductive hydroglycosylation of alkynes

C-Glycosyl peptides/proteins are metabolically stable mimics of the native glycopeptides/proteins bearing O/N-glycosidic linkages, and are thus of great therapeutical potential. Herein, we disclose a protocol for the syntheses of vinyl C-glycosyl amino acids and peptides, employing a nickel-catalyze...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yan-Hua, Xia, Yu-Nong, Gulzar, Tayyab, Wei, Bingcheng, Li, Haotian, Zhu, Dapeng, Hu, Zhifei, Xu, Peng, Yu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363649/
https://www.ncbi.nlm.nih.gov/pubmed/34389709
http://dx.doi.org/10.1038/s41467-021-25127-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363649/
https://www.ncbi.nlm.nih.gov/pubmed/34389709
http://dx.doi.org/10.1038/s41467-021-25127-z

Ejemplares similares