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PD-L1(+) and XCR1(+) dendritic cells are region-specific regulators of gut homeostasis

The intestinal mucosa constitutes an environment of closely regulated immune cells. Dendritic cells (DC) interact with the gut microbiome and antigens and are important in maintaining gut homeostasis. Here, we investigate DC transcriptome, phenotype and function in five anatomical locations of the g...

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Detalles Bibliográficos
Autores principales: Moreira, Thais G., Mangani, Davide, Cox, Laura M., Leibowitz, Jeffrey, Lobo, Eduardo. L. C., Oliveira, Mariana A., Gauthier, Christian D., Nakagaki, Brenda N., Willocq, Valerie, Song, Anya, Guo, Lydia, Lima, David C. A., Murugaiyan, Gopal, Butovsky, Oleg, Gabriely, Galina, Anderson, Ana C., Rezende, Rafael M., Faria, Ana Maria C., Weiner, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363668/
https://www.ncbi.nlm.nih.gov/pubmed/34389726
http://dx.doi.org/10.1038/s41467-021-25115-3