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Predicting Inter-individual Variability During Lipid Resuscitation of Bupivacaine Cardiotoxicity in Rats: A Virtual Population Modeling Study

INTRODUCTION: Intravenous lipid emulsions (ILE) have been credited for successful resuscitation in drug intoxication cases where other cardiac life-support methods have failed. However, inter-individual variability can function as a confounder that challenges our ability to define the scope of effic...

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Detalles Bibliográficos
Autores principales: McDaniel, Matthew, Flores, Kevin B., Akpa, Belinda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363697/
https://www.ncbi.nlm.nih.gov/pubmed/34279844
http://dx.doi.org/10.1007/s40268-021-00353-4