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Predicting Inter-individual Variability During Lipid Resuscitation of Bupivacaine Cardiotoxicity in Rats: A Virtual Population Modeling Study
INTRODUCTION: Intravenous lipid emulsions (ILE) have been credited for successful resuscitation in drug intoxication cases where other cardiac life-support methods have failed. However, inter-individual variability can function as a confounder that challenges our ability to define the scope of effic...
Autores principales: | McDaniel, Matthew, Flores, Kevin B., Akpa, Belinda S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363697/ https://www.ncbi.nlm.nih.gov/pubmed/34279844 http://dx.doi.org/10.1007/s40268-021-00353-4 |
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