Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation

The type I interferon (IFN) pathway is a key component of innate immune response upon invasion of foreign pathogens. It is also under precise control to prevent excessive upregulation and undesired inflammation cascade. In the present study, we report that Riok3, an atypical kinase, negatively regul...

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Detalles Bibliográficos
Autores principales: Shen, Yong, Tang, Kejun, Chen, Dongdong, Hong, Mengying, Sun, Fangfang, Wang, SaiSai, Ke, Yuehai, Wu, Tingting, Sun, Ren, Qian, Jing, Du, Yushen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363743/
https://www.ncbi.nlm.nih.gov/pubmed/34161773
http://dx.doi.org/10.1016/j.celrep.2021.109272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363743/
https://www.ncbi.nlm.nih.gov/pubmed/34161773
http://dx.doi.org/10.1016/j.celrep.2021.109272

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