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Chemically induced hypoxia by dimethyloxalylglycine (DMOG)-loaded nanoporous silica nanoparticles supports endothelial tube formation by sustained VEGF release from adipose tissue-derived stem cells

Inadequate vascularization leading to insufficient oxygen and nutrient supply in deeper layers of bioartificial tissues remains a limitation in current tissue engineering approaches to which pre-vascularization offers a promising solution. Hypoxia triggering pre-vascularization by enhanced vascular...

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Detalles Bibliográficos
Autores principales: Zippusch, Sarah, Besecke, Karen F W, Helms, Florian, Klingenberg, Melanie, Lyons, Anne, Behrens, Peter, Haverich, Axel, Wilhelmi, Mathias, Ehlert, Nina, Böer, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363767/
https://www.ncbi.nlm.nih.gov/pubmed/34408911
http://dx.doi.org/10.1093/rb/rbab039