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Mid-pregnancy maternal immune activation increases Pax6-positive and Tbr2-positive neural progenitor cells and causes integrated stress response in the fetal brain in a mouse model of maternal viral infection

Maternal immune activation (MIA) in midpregnancy is a risk factor for neurodevelopmental disorders. Improper brain development may cause malformations of the brain; maldevelopment induced by MIA may lead to a pathology-related phenotype. In this study, a single intraperitoneal injection of 20 mg/kg...

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Detalles Bibliográficos
Autores principales: Tsukada, Tsuyoshi, Sakata-Haga, Hiromi, Shimada, Hiroki, Shoji, Hiroki, Hatta, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363822/
https://www.ncbi.nlm.nih.gov/pubmed/34409402
http://dx.doi.org/10.1016/j.ibneur.2021.07.003