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Mid-pregnancy maternal immune activation increases Pax6-positive and Tbr2-positive neural progenitor cells and causes integrated stress response in the fetal brain in a mouse model of maternal viral infection
Maternal immune activation (MIA) in midpregnancy is a risk factor for neurodevelopmental disorders. Improper brain development may cause malformations of the brain; maldevelopment induced by MIA may lead to a pathology-related phenotype. In this study, a single intraperitoneal injection of 20 mg/kg...
Autores principales: | Tsukada, Tsuyoshi, Sakata-Haga, Hiromi, Shimada, Hiroki, Shoji, Hiroki, Hatta, Toshihisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363822/ https://www.ncbi.nlm.nih.gov/pubmed/34409402 http://dx.doi.org/10.1016/j.ibneur.2021.07.003 |
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