Unbiased Proteomic and Phosphoproteomic Analysis Identifies Response Signatures and Novel Susceptibilities After Combined MEK and mTOR Inhibition in BRAF(V600E) Mutant Glioma

The mitogen-activated protein kinase pathway is one of the most frequently altered pathways in cancer. It is involved in the control of cell proliferation, invasion, and metabolism, and can cause resistance to therapy. A number of aggressive malignancies, including melanoma, colon cancer, and glioma...

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Detalles Bibliográficos
Autores principales: Maxwell, Micah J., Arnold, Antje, Sweeney, Heather, Chen, Lijun, Lih, Tung-Shing M., Schnaubelt, Michael, Eberhart, Charles G., Rubens, Jeffrey A., Zhang, Hui, Clark, David J., Raabe, Eric H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363840/
https://www.ncbi.nlm.nih.gov/pubmed/34298159
http://dx.doi.org/10.1016/j.mcpro.2021.100123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363840/
https://www.ncbi.nlm.nih.gov/pubmed/34298159
http://dx.doi.org/10.1016/j.mcpro.2021.100123

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