Synthesis and Antiplatelet and Anticoagulant Activity of Thietane-Containing 2-(5-Bromo-2,4-Dihydro-3-Oxo-1,2,4-Triazolyl-4)Acetate Salts

Sulfone II was synthesized via oxidation of ethyl 2-[5-bromo-2,4-dihydro-3-oxo-2-(thietanyl-3)-1,2,4-triazolyl- 4]acetate (I) by H(2)O(2). Hydrolysis of esters I and II synthesized 2-[5-bromo-2,4-dihydro- 3-oxo-2-(thietanyl-3)-1,2,4-triazolyl-4]- and 2-[5-bromo-2,4-dihydro-3-oxo-2-(1,1-dioxothietany...

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Detalles Bibliográficos
Autores principales: Gurevich, K. G., Urakov, A. L., Rozit, G. A., Klen, E. É., Samorodov, A. V., Khaliullin, F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Search for New Drugs
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363854/
https://www.ncbi.nlm.nih.gov/pubmed/34413551
http://dx.doi.org/10.1007/s11094-021-02437-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363854/
https://www.ncbi.nlm.nih.gov/pubmed/34413551
http://dx.doi.org/10.1007/s11094-021-02437-6

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