Defective insulin-stimulated GLUT4 translocation in brown adipocytes induces systemic glucose homeostasis dysregulation independent of thermogenesis in female mice

OBJECTIVE: Recent studies indicate that brown adipose tissue, in addition to its role in thermogenesis, has a role in the regulation of whole-body metabolism. Here we characterize the metabolic effects of deleting Rab10, a protein key for insulin stimulation of glucose uptake into white adipocytes,...

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Detalles Bibliográficos
Autores principales: Picatoste, Belén, Yammine, Lucie, Leahey, Rosemary A., Soares, David, Johnson, Emma F., Cohen, Paul, McGraw, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363886/
https://www.ncbi.nlm.nih.gov/pubmed/34303022
http://dx.doi.org/10.1016/j.molmet.2021.101305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363886/
https://www.ncbi.nlm.nih.gov/pubmed/34303022
http://dx.doi.org/10.1016/j.molmet.2021.101305

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