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Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum

Extracellular vesicles (EVs) are mediators of intercellular communication under both healthy and pathological conditions, including the induction of pro‐metastatic traits, but it is not yet known how and where functional cargoes of EVs are delivered to their targets in host cell compartments. We hav...

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Detalles Bibliográficos
Autores principales: Santos, Mark F., Rappa, Germana, Karbanová, Jana, Fontana, Simona, Bella, Maria Antonietta Di, Pope, Marshall R., Parrino, Barbara, Cascioferro, Stella Maria, Vistoli, Giulio, Diana, Patrizia, Cirrincione, Girolamo, Arena, Goffredo O., Woo, Gyunghwi, Huang, Kevin, Huynh, Tony, Moschetti, Marta, Alessandro, Riccardo, Corbeil, Denis, Lorico, Aurelio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363911/
https://www.ncbi.nlm.nih.gov/pubmed/34429859
http://dx.doi.org/10.1002/jev2.12132