Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8 (+) T cell infiltrate

Colorectal cancer (CRC) remains a leading cause of cancer mortality. Here, we define the colonic epithelial expression of cathelicidin (LL‐37) in CRC. Cathelicidin exerts pleotropic effects including anti‐microbial and immunoregulatory functions. Genetic knockout of cathelicidin led to increased siz...

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Detalles Bibliográficos
Autores principales: Porter, Ross J, Murray, Graeme I, Alnabulsi, Abdo, Humphries, Matthew P, James, Jacqueline A, Salto‐Tellez, Manuel, Craig, Stephanie G, Wang, Ji M, Yoshimura, Teizo, McLean, Mairi H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363930/
https://www.ncbi.nlm.nih.gov/pubmed/33988317
http://dx.doi.org/10.1002/cjp2.222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363930/
https://www.ncbi.nlm.nih.gov/pubmed/33988317
http://dx.doi.org/10.1002/cjp2.222

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