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Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8 (+) T cell infiltrate
Colorectal cancer (CRC) remains a leading cause of cancer mortality. Here, we define the colonic epithelial expression of cathelicidin (LL‐37) in CRC. Cathelicidin exerts pleotropic effects including anti‐microbial and immunoregulatory functions. Genetic knockout of cathelicidin led to increased siz...
Autores principales: | Porter, Ross J, Murray, Graeme I, Alnabulsi, Abdo, Humphries, Matthew P, James, Jacqueline A, Salto‐Tellez, Manuel, Craig, Stephanie G, Wang, Ji M, Yoshimura, Teizo, McLean, Mairi H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363930/ https://www.ncbi.nlm.nih.gov/pubmed/33988317 http://dx.doi.org/10.1002/cjp2.222 |
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