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Activation of G protein-coupled estradiol receptor 1 in the dorsolateral striatum enhances motivation for cocaine and drug-induced reinstatement in female but not male rats

BACKGROUND: Estradiol potentiates drug-taking behaviors, including motivation to self-administer cocaine and reinstatement of drug-seeking after extinction in females, but not males. The dorsolateral stratum (DLS) is a region of the brain implicated in mediating drug-seeking behaviors and, more spec...

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Detalles Bibliográficos
Autores principales: Quigley, Jacqueline A., Logsdon, Molly K., Graham, Brianna C., Beaudoin, Kendra G., Becker, Jill B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364009/
https://www.ncbi.nlm.nih.gov/pubmed/34391470
http://dx.doi.org/10.1186/s13293-021-00389-w