Dock2 affects the host susceptibility to Citrobacter rodentium infection through regulating gut microbiota

BACKGROUND: Dysregulated gut microbiota is one of major pathogenic factors in the development of colitis. Dock2 acts as a guanine nucleotide exchange factor (GEF) and activates small G protein RAC1. Our previous study showed that, compared to wild type (WT) mice, Dock2(−/−) mice were more susceptibl...

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Detalles Bibliográficos
Autores principales: Xie, Yuan, Chen, Jun, Wu, Bing, He, Tiansheng, Xie, Lu, Liu, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364044/
https://www.ncbi.nlm.nih.gov/pubmed/34391464
http://dx.doi.org/10.1186/s13099-021-00449-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364044/
https://www.ncbi.nlm.nih.gov/pubmed/34391464
http://dx.doi.org/10.1186/s13099-021-00449-x

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