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Dock2 affects the host susceptibility to Citrobacter rodentium infection through regulating gut microbiota
BACKGROUND: Dysregulated gut microbiota is one of major pathogenic factors in the development of colitis. Dock2 acts as a guanine nucleotide exchange factor (GEF) and activates small G protein RAC1. Our previous study showed that, compared to wild type (WT) mice, Dock2(−/−) mice were more susceptibl...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364044/ https://www.ncbi.nlm.nih.gov/pubmed/34391464 http://dx.doi.org/10.1186/s13099-021-00449-x |