Sleep loss drives acetylcholine- and somatostatin interneuron–mediated gating of hippocampal activity to inhibit memory consolidation

Sleep loss disrupts consolidation of hippocampus-dependent memory. To characterize effects of learning and sleep loss, we quantified activity-dependent phosphorylation of ribosomal protein S6 (pS6) across the dorsal hippocampus of mice. We find that pS6 is enhanced in dentate gyrus (DG) following si...

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Detalles Bibliográficos
Autores principales: Delorme, James, Wang, Lijing, Kuhn, Femke Roig, Kodoth, Varna, Ma, Jingqun, Martinez, Jessy D., Raven, Frank, Toth, Brandon A., Balendran, Vinodh, Vega Medina, Alexis, Jiang, Sha, Aton, Sara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364159/
https://www.ncbi.nlm.nih.gov/pubmed/34344824
http://dx.doi.org/10.1073/pnas.2019318118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364159/
https://www.ncbi.nlm.nih.gov/pubmed/34344824
http://dx.doi.org/10.1073/pnas.2019318118

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