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Ras-like Gem GTPase induced by Npas4 promotes activity-dependent neuronal tolerance for ischemic stroke

Ischemic stroke, which results in loss of neurological function, initiates a complex cascade of pathological events in the brain, largely driven by excitotoxic Ca(2+) influx in neurons. This leads to cortical spreading depolarization, which induces expression of genes involved in both neuronal death...

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Detalles Bibliográficos
Autores principales: Takahashi, Hiroo, Asahina, Ryo, Fujioka, Masayuki, Matsui, Takeshi K., Kato, Shigeki, Mori, Eiichiro, Hioki, Hiroyuki, Yamamoto, Tohru, Kobayashi, Kazuto, Tsuboi, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364162/
https://www.ncbi.nlm.nih.gov/pubmed/34349016
http://dx.doi.org/10.1073/pnas.2018850118