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Ras-like Gem GTPase induced by Npas4 promotes activity-dependent neuronal tolerance for ischemic stroke
Ischemic stroke, which results in loss of neurological function, initiates a complex cascade of pathological events in the brain, largely driven by excitotoxic Ca(2+) influx in neurons. This leads to cortical spreading depolarization, which induces expression of genes involved in both neuronal death...
Autores principales: | Takahashi, Hiroo, Asahina, Ryo, Fujioka, Masayuki, Matsui, Takeshi K., Kato, Shigeki, Mori, Eiichiro, Hioki, Hiroyuki, Yamamoto, Tohru, Kobayashi, Kazuto, Tsuboi, Akio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364162/ https://www.ncbi.nlm.nih.gov/pubmed/34349016 http://dx.doi.org/10.1073/pnas.2018850118 |
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