A squalene–hopene cyclase in Schizosaccharomyces japonicus represents a eukaryotic adaptation to sterol-limited anaerobic environments

Biosynthesis of sterols, which are key constituents of canonical eukaryotic membranes, requires molecular oxygen. Anaerobic protists and deep-branching anaerobic fungi are the only eukaryotes in which a mechanism for sterol-independent growth has been elucidated. In these organisms, tetrahymanol, fo...

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Detalles Bibliográficos
Autores principales: Bouwknegt, Jonna, Wiersma, Sanne J., Ortiz-Merino, Raúl A., Doornenbal, Eline S. R., Buitenhuis, Petrik, Giera, Martin, Müller, Christoph, Pronk, Jack T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364164/
https://www.ncbi.nlm.nih.gov/pubmed/34353908
http://dx.doi.org/10.1073/pnas.2105225118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364164/
https://www.ncbi.nlm.nih.gov/pubmed/34353908
http://dx.doi.org/10.1073/pnas.2105225118

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