Elucidation of an anaerobic pathway for metabolism of l-carnitine–derived γ-butyrobetaine to trimethylamine in human gut bacteria

Trimethylamine (TMA) is an important gut microbial metabolite strongly associated with human disease. There are prominent gaps in our understanding of how TMA is produced from the essential dietary nutrient l-carnitine, particularly in the anoxic environment of the human gut where oxygen-dependent l...

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Detalles Bibliográficos
Autores principales: Rajakovich, Lauren J., Fu, Beverly, Bollenbach, Maud, Balskus, Emily P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364193/
https://www.ncbi.nlm.nih.gov/pubmed/34362844
http://dx.doi.org/10.1073/pnas.2101498118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364193/
https://www.ncbi.nlm.nih.gov/pubmed/34362844
http://dx.doi.org/10.1073/pnas.2101498118

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