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Developing urinary pyrrole–amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human

Pyrrolizidine alkaloids (PAs) have been found in over 6000 plants worldwide and represent the most common hepatotoxic phytotoxins. Currently, a definitive diagnostic method for PA-induced liver injury (PA-ILI) is lacking. In the present study, using a newly developed analytical method, we identified...

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Detalles Bibliográficos
Autores principales: Zhu, Lin, Zhang, Chunyuan, Zhang, Wei, Xia, Qingsu, Ma, Jiang, He, Xin, He, Yisheng, Fu, Peter P., Jia, Wei, Zhuge, Yuzheng, Lin, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364305/
https://www.ncbi.nlm.nih.gov/pubmed/34390356
http://dx.doi.org/10.1007/s00204-021-03129-6