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Tracking and interpreting long-range chromatin interactions with super-resolution live-cell imaging

Mammalian genomes are organized and regulated through long-range chromatin interactions. Structural loops formed by CCCTC-binding factor (CTCF) and cohesin fold the genome into domains, while enhancers interact with promoters across vast genomic distances to regulate gene expression. Although genomi...

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Detalles Bibliográficos
Autores principales: Brandão, Hugo B., Gabriele, Michele, Hansen, Anders S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364313/
https://www.ncbi.nlm.nih.gov/pubmed/33310227
http://dx.doi.org/10.1016/j.ceb.2020.11.002