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Tracking and interpreting long-range chromatin interactions with super-resolution live-cell imaging
Mammalian genomes are organized and regulated through long-range chromatin interactions. Structural loops formed by CCCTC-binding factor (CTCF) and cohesin fold the genome into domains, while enhancers interact with promoters across vast genomic distances to regulate gene expression. Although genomi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364313/ https://www.ncbi.nlm.nih.gov/pubmed/33310227 http://dx.doi.org/10.1016/j.ceb.2020.11.002 |