Acquisition of the mcr-1 Gene Lowers the Target Mutation to Impede the Evolution of a High-Level Colistin-Resistant Mutant in Escherichia coli

OBJECTIVE: The spread of the plasmid-mediated colistin resistance gene mcr-1 poses a significant public health threat. Little information is available on the development of high-level colistin-resistant mutants (HLCRMs) in MCR-1-producing Escherichia coli (MCRPEC). The present study was designed to...

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Detalles Bibliográficos
Autores principales: Huang, Chen, Shi, Qingyi, Zhang, Shuntian, Wu, Hongcheng, Xiao, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364431/
https://www.ncbi.nlm.nih.gov/pubmed/34408448
http://dx.doi.org/10.2147/IDR.S324303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364431/
https://www.ncbi.nlm.nih.gov/pubmed/34408448
http://dx.doi.org/10.2147/IDR.S324303

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