BRD4 inhibition promotes TRAIL-induced apoptosis by suppressing the transcriptional activity of NF-κB in NSCLC

Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and agonistic antibodies against TRAIL death receptors (DR) can induce apoptosis preferentially in tumor cells while causing virtually no damage to normal cells. However, their therapeutic potential is limited by occurring resistance in...

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Detalles Bibliográficos
Autores principales: Shi, Liu, Xiong, Yu, Hu, Xiaoyan, Wang, Zhihao, Xie, Conghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364464/
https://www.ncbi.nlm.nih.gov/pubmed/34400879
http://dx.doi.org/10.7150/ijms.60776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364464/
https://www.ncbi.nlm.nih.gov/pubmed/34400879
http://dx.doi.org/10.7150/ijms.60776

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