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Insulitis in the pancreas of non-diabetic organ donors under age 25 years with multiple circulating autoantibodies against islet cell antigens

Autoantibodies against islet cell antigens are routinely used to identify subjects at increased risk of symptomatic type 1 diabetes, but their relation to the intra-islet pathogenetic process that leads to positivity for these markers is poorly understood. We screened 556 non-diabetic organ donors (...

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Detalles Bibliográficos
Autores principales: Smeets, Silke, De Paep, Diedert Luc, Stangé, Geert, Verhaeghen, Katrijn, Van der Auwera, Bart, Keymeulen, Bart, Weets, Ilse, Ling, Zhidong, in’t Veld, Peter, Gorus, Frans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364522/
https://www.ncbi.nlm.nih.gov/pubmed/33594586
http://dx.doi.org/10.1007/s00428-021-03055-z