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CPT1α maintains phenotype of tubules via mitochondrial respiration during kidney injury and repair

Impaired energy metabolism in proximal tubular epithelial cells (PTECs) is strongly associated with various kidney diseases. Here, we characterized proximal tubular phenotype alternations during kidney injury and repair in a mouse model of folic acid nephropathy, in parallel, identified carnitine pa...

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Detalles Bibliográficos
Autores principales: Yuan, Qi, Lv, Yunhui, Ding, Hao, Ke, Qingqing, Shi, Caifeng, Luo, Jing, Jiang, Lei, Yang, Junwei, Zhou, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364553/
https://www.ncbi.nlm.nih.gov/pubmed/34392303
http://dx.doi.org/10.1038/s41419-021-04085-w