NKG2D-CAR-transduced natural killer cells efficiently target multiple myeloma

CAR-T-cell therapy against MM currently shows promising results, but usually with serious toxicities. CAR-NK cells may exert less toxicity when redirected against resistant myeloma cells. CARs can be designed through the use of receptors, such as NKG2D, which recognizes a wide range of ligands to pr...

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Detalles Bibliográficos
Autores principales: Leivas, Alejandra, Valeri, Antonio, Córdoba, Laura, García-Ortiz, Almudena, Ortiz, Alejandra, Sánchez-Vega, Laura, Graña-Castro, Osvaldo, Fernández, Lucía, Carreño-Tarragona, Gonzalo, Pérez, Manuel, Megías, Diego, Paciello, María Liz, Sánchez-Pina, Jose, Pérez-Martínez, Antonio, Lee, Dean A., Powell, Daniel J., Río, Paula, Martínez-López, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364555/
https://www.ncbi.nlm.nih.gov/pubmed/34392311
http://dx.doi.org/10.1038/s41408-021-00537-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364555/
https://www.ncbi.nlm.nih.gov/pubmed/34392311
http://dx.doi.org/10.1038/s41408-021-00537-w

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