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Targeting of IL-10R on acute myeloid leukemia blasts with chimeric antigen receptor-expressing T cells

Acute myeloid leukemia (AML) is a biologically and clinically heterogeneous disease with a dismal prognosis and limited treatment options. Chimeric antigen receptor (CAR) T cells have achieved unprecedented clinical responses in patients with B cell malignancies but a dismal consequences in AML. In...

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Detalles Bibliográficos
Autores principales: Chen, Nianci, Xu, Yingxi, Mou, Junli, Rao, Qing, Xing, Haiyan, Tian, Zheng, Tang, Kejing, Wang, Min, Wang, Jiangxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364556/
https://www.ncbi.nlm.nih.gov/pubmed/34392305
http://dx.doi.org/10.1038/s41408-021-00536-x