A model for COVID-19-induced dysregulation of ACE2 shedding by ADAM17

The angiotensin Converting Enzyme 2 (ACE2) receptor is a key component of the renin-angiotensin-aldesterone system (RAAS) that mediates numerous effects in the cardiovascular system. It is also the cellular point of contact for the coronavirus spike protein. Cleavage of the receptor is both importan...

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Detalles Bibliográficos
Autores principales: Healy, Eamonn F., Lilic, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364680/
https://www.ncbi.nlm.nih.gov/pubmed/34416436
http://dx.doi.org/10.1016/j.bbrc.2021.08.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364680/
https://www.ncbi.nlm.nih.gov/pubmed/34416436
http://dx.doi.org/10.1016/j.bbrc.2021.08.040

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