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A model for COVID-19-induced dysregulation of ACE2 shedding by ADAM17
The angiotensin Converting Enzyme 2 (ACE2) receptor is a key component of the renin-angiotensin-aldesterone system (RAAS) that mediates numerous effects in the cardiovascular system. It is also the cellular point of contact for the coronavirus spike protein. Cleavage of the receptor is both importan...
Autores principales: | Healy, Eamonn F., Lilic, Marko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364680/ https://www.ncbi.nlm.nih.gov/pubmed/34416436 http://dx.doi.org/10.1016/j.bbrc.2021.08.040 |
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