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Chaihu-Shugan-San (Shihosogansan) alleviates restraint stress-generated anxiety and depression in mice by regulating NF-κB-mediated BDNF expression through the modulation of gut microbiota

BACKGROUND: Chaihu-Shugan-San (CSS, named Shihosogansan in Korean), a Chinese traditional medicine, is frequently used to treat anxiety and depression. Psychiatric disorders including depression are associated with gut dysbiosis. Therefore, to comprehend gut microbiota-involved anti-depressive effec...

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Detalles Bibliográficos
Autores principales: Han, Sang-Kap, Kim, Jeon-Kyung, Park, Hee-Seo, Shin, Yeun-Jeong, Kim, Dong-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364688/
https://www.ncbi.nlm.nih.gov/pubmed/34391441
http://dx.doi.org/10.1186/s13020-021-00492-5