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Elevated exosome-derived miRNAs predict osimertinib resistance in non-small cell lung cancer

BACKGROUND: Non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations will inevitably develop drug resistance after being treated with the third-generation EGFR-tyrosine kinase inhibitor (TKI), osimertinib. Recently, the drug resistance information transmitte...

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Detalles Bibliográficos
Autores principales: Li, Xinying, Chen, Cen, Wang, Zimu, Liu, Jiaxin, Sun, Wei, Shen, Kaikai, Lv, Yanling, Zhu, Suhua, Zhan, Ping, Lv, Tangfeng, Song, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364701/
https://www.ncbi.nlm.nih.gov/pubmed/34391435
http://dx.doi.org/10.1186/s12935-021-02075-8