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Complement factor D is linked to platelet activation in human and rodent sepsis

BACKGROUND: The complement factor D (CFD) exerts a regulatory role during infection. However, its physiological function in coagulopathy and its impact on the course of an infection remains unclear. MATERIALS: Wild-type and CFD-deficient mice (n = 91) were subjected to cecal ligation and puncture to...

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Detalles Bibliográficos
Autores principales: Sommerfeld, O., Dahlke, K., Sossdorf, M., Claus, R. A., Scherag, A., Bauer, M., Bloos, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364893/
https://www.ncbi.nlm.nih.gov/pubmed/34396466
http://dx.doi.org/10.1186/s40635-021-00405-8