Generation and Characterization of Torudokimab (LY3375880): A Monoclonal Antibody That Neutralizes Interleukin-33

BACKGROUND: Interleukin-33 (IL-33) is an alarmin that is released following cellular damage, mechanical injury, or necrosis. It is a member of the IL-1 family and binds to a heterodimer receptor consisting of ST2 and IL-1RAP to induce the production of a wide range of cellular mediators, including t...

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Detalles Bibliográficos
Autores principales: Okragly, Angela J, Corwin, Katie Brannon, Elia, Marikka, He, Dongmei, Schroeder, Oliver, Zhang, Qing, Shiyanova, Tatiyana, Bright, Stuart, Dicker, Sarah B, Chlewicki, Lukasz, Truhlar, Stephanie M E, Davies, Julian, Patel, Chetan N, Benschop, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364917/
https://www.ncbi.nlm.nih.gov/pubmed/34408465
http://dx.doi.org/10.2147/JIR.S320287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364917/
https://www.ncbi.nlm.nih.gov/pubmed/34408465
http://dx.doi.org/10.2147/JIR.S320287

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