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Intratubular, Intracellular, and Mitochondrial Angiotensin II/AT(1) (AT1a) Receptor/NHE3 Signaling Plays a Critical Role in Angiotensin II-Induced Hypertension and Kidney Injury

Hypertension is well recognized to be the most important risk factor for cardiovascular diseases, stroke, and end-stage kidney failure. A quarter of the world’s adult populations and 46% of the US adults develop hypertension and currently require antihypertensive treatments. Only 50% of hypertensive...

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Detalles Bibliográficos
Autores principales: Li, Xiao Chun, Wang, Chih-Hong, Leite, Ana Paula Oliveira, Zhuo, Jia Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364949/
https://www.ncbi.nlm.nih.gov/pubmed/34408663
http://dx.doi.org/10.3389/fphys.2021.702797