Developing human pluripotent stem cell-based cerebral organoids with a controllable microglia ratio for modeling brain development and pathology

Microglia play critical roles in brain development, homeostasis, and disease. Microglia in animal models cannot accurately model human microglia due to notable transcriptomic and functional differences between human and other animal microglia. Incorporating human pluripotent stem cell (hPSC)-derived...

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Detalles Bibliográficos
Autores principales: Xu, Ranjie, Boreland, Andrew J., Li, Xiaoxi, Erickson, Caroline, Jin, Mengmeng, Atkins, Colm, Pang, Zhiping P., Daniels, Brian P., Jiang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365109/
https://www.ncbi.nlm.nih.gov/pubmed/34297942
http://dx.doi.org/10.1016/j.stemcr.2021.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365109/
https://www.ncbi.nlm.nih.gov/pubmed/34297942
http://dx.doi.org/10.1016/j.stemcr.2021.06.011

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