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Protocol for simulating macrophage signal transduction and phenotype polarization using a large-scale mechanistic computational model

The ability to measure and analyze the complex dynamic multi-marker features of macrophages is critical for the understanding of their diverse phenotypes and functions in health and disease. To that end, we have recently developed a multi-pathway computational model that for the first time enables a...

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Detalles Bibliográficos
Autores principales: Zhao, Chen, Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365221/
https://www.ncbi.nlm.nih.gov/pubmed/34430914
http://dx.doi.org/10.1016/j.xpro.2021.100739