EZH2/EHMT2 Histone Methyltransferases Inhibit the Transcription of DLX5 and Promote the Transformation of Myelodysplastic Syndrome to Acute Myeloid Leukemia

Myelodysplastic syndrome (MDS) is characterized by clonal hematopoiesis and impaired differentiation, and may develop to acute myeloid leukemia (AML). We explored the mechanism of histone methyltransferase EZH2/EHMT2 during the transformation of MDS into AML. Expression of EZH2/EHMT2 in patients and...

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Detalles Bibliográficos
Autores principales: Zheng, Zhuanzhen, Li, Ling, Li, Guoxia, Zhang, Yaofang, Dong, Chunxia, Ren, Fanggang, Chen, Wenliang, Ma, Yanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365305/
https://www.ncbi.nlm.nih.gov/pubmed/34409024
http://dx.doi.org/10.3389/fcell.2021.619795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365305/
https://www.ncbi.nlm.nih.gov/pubmed/34409024
http://dx.doi.org/10.3389/fcell.2021.619795

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