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Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease

BACKGROUND: Liver fibrosis risk is a heritable trait, the outcome of which is the net deposition of extracellular matrix by hepatic stellate cell-derived myofibroblasts. Whereas nucleotide sequence variations have been extensively studied in liver fibrosis, the role of copy number variations (CNV) i...

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Detalles Bibliográficos
Autores principales: Metwally, Mayada, Bayoumi, Ali, Khan, Anis, Adams, Leon A., Aller, Rocio, García-Monzón, Carmelo, Arias-Loste, María Teresa, Bugianesi, Elisabetta, Miele, Luca, Anna, Alisi, Latchoumanin, Olivier, Han, Shuanglin, Alenizi, Shafi, Sharkawy, Rasha EL, Elattar, Afaf, Gallego-Durán, Rocio, Fischer, Janett, Berg, Thomas, Liddle, Christopher, Romero-Gomez, Manuel, George, Jacob, Eslam, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365315/
https://www.ncbi.nlm.nih.gov/pubmed/34388518
http://dx.doi.org/10.1016/j.ebiom.2021.103521