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Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease
BACKGROUND: Liver fibrosis risk is a heritable trait, the outcome of which is the net deposition of extracellular matrix by hepatic stellate cell-derived myofibroblasts. Whereas nucleotide sequence variations have been extensively studied in liver fibrosis, the role of copy number variations (CNV) i...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365315/ https://www.ncbi.nlm.nih.gov/pubmed/34388518 http://dx.doi.org/10.1016/j.ebiom.2021.103521 |