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Fast and Efficient Genome Editing of Human FOXP3(+) Regulatory T Cells

FOXP3(+) regulatory T cells (Tregs) are central for maintaining peripheral tolerance and immune homeostasis. Because of their immunosuppressive characteristics, Tregs are a potential therapeutic target in various diseases such as autoimmunity, transplantation and infectious diseases like COVID-19. N...

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Detalles Bibliográficos
Autores principales: Van Zeebroeck, Lauren, Arroyo Hornero, Rebeca, Côrte-Real, Beatriz F., Hamad, Ibrahim, Meissner, Torsten B., Kleinewietfeld, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365355/
https://www.ncbi.nlm.nih.gov/pubmed/34408743
http://dx.doi.org/10.3389/fimmu.2021.655122