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Structural determinants and distribution of phosphate specificity in ribonucleotide reductases

Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to the corresponding deoxyribonucleotides, the building blocks of DNA. RNRs are specific for either ribonucleoside diphosphates or triphosphates as substrates. As far as is known, oxygen-dependent class I RNRs (NrdAB) all red...

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Detalles Bibliográficos
Autores principales: Schell, Eugen, Nouairia, Ghada, Steiner, Elisabeth, Weber, Niclas, Lundin, Daniel, Loderer, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365446/
https://www.ncbi.nlm.nih.gov/pubmed/34314684
http://dx.doi.org/10.1016/j.jbc.2021.101008