Protease-activated receptor-2 promotes osteogenesis in skeletal mesenchymal stem cells at the expense of adipogenesis: Involvement of interleukin-6

Bone marrow mesenchymal stem cells (MSCs) give rise to osteoblasts and adipocytes, with an inverse relationship between the two. The MSCs from protease-activated receptor-2 knockout (PAR(2) KO) mice have a reduced capacity to generate osteoblasts. Here we describe the observation that PAR(2) KO oste...

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Detalles Bibliográficos
Autores principales: Sanaei, R., Kularathna, P.K., Taghavi, N., Hooper, J.D., Pagel, C.N., Mackie, E.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365448/
https://www.ncbi.nlm.nih.gov/pubmed/34430676
http://dx.doi.org/10.1016/j.bonr.2021.101113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365448/
https://www.ncbi.nlm.nih.gov/pubmed/34430676
http://dx.doi.org/10.1016/j.bonr.2021.101113

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