Cargando…

Protease-activated receptor-2 promotes osteogenesis in skeletal mesenchymal stem cells at the expense of adipogenesis: Involvement of interleukin-6

Bone marrow mesenchymal stem cells (MSCs) give rise to osteoblasts and adipocytes, with an inverse relationship between the two. The MSCs from protease-activated receptor-2 knockout (PAR(2) KO) mice have a reduced capacity to generate osteoblasts. Here we describe the observation that PAR(2) KO oste...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sanaei, R., Kularathna, P.K., Taghavi, N., Hooper, J.D., Pagel, C.N., Mackie, E.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365448/ https://www.ncbi.nlm.nih.gov/pubmed/34430676 http://dx.doi.org/10.1016/j.bonr.2021.101113

Ejemplares similares

Chemerin deficiency regulates adipogenesis is depot different through TIMP1
por: Huang, Cheng-Long, et al.
Publicado: (2020)

Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis
por: Dong, Bingzi, et al.
Publicado: (2022)

PVA/pectin composite hydrogels inducing osteogenesis for bone regeneration
por: Hu, Ziwei, et al.
Publicado: (2022)

Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis
por: Xiao, Yinbo, et al.
Publicado: (2022)

Methoxy polyethylene glycol modification promotes adipogenesis by inducing the production of regulatory T cells in xenogeneic acellular adipose matrix
por: Liu, Kaiyang, et al.
Publicado: (2021)

Affinity Based Nano-Magnetic Particles for Purification of Recombinant Proteins in Form of Inclusion Body
por: Seyedinkhorasani, Masoud, et al.
Publicado: (2020)

Granular honeycomb scaffolds composed of carbonate apatite for simultaneous intra- and inter-granular osteogenesis and angiogenesis
por: Hayashi, Koichiro, et al.
Publicado: (2022)

Putative papain‐related thiol proteases of positive‐strand RNA viruses Identification of rubi‐ and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi‐, α‐ and coronaviruses
por: Gorbalenya, Alexander E., et al.
Publicado: (1991)

Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis
por: Zhang, Jingwei, et al.
Publicado: (2017)

Janus electro-microenvironment membrane with surface-selective osteogenesis/gingival healing ability for guided bone regeneration
por: Lai, Chunhua, et al.
Publicado: (2022)

The design of strut/TPMS-based pore geometries in bioceramic scaffolds guiding osteogenesis and angiogenesis in bone regeneration
por: Li, Yifan, et al.
Publicado: (2023)

Effect of high cyclic hydrostatic pressure on osteogenesis of mesenchymal stem cells cultured in liquefied micro-compartments
por: Ghasemzadeh-Hasankolaei, Maryam, et al.
Publicado: (2023)

3D-Printed PCL/Zn scaffolds for bone regeneration with a dose-dependent effect on osteogenesis and osteoclastogenesis
por: Wang, Siyi, et al.
Publicado: (2022)

Evaluation of Serum Interleukin-21 and HLA-C1 Polymorphism in Pediatrician Hematopoietic Stem Cell Transplantation for Early Diagnosis of Acute Graft-Versus-Host Disease
por: Sehati, Nasrin, et al.
Publicado: (2017)

Emodin enhances osteogenesis and inhibits adipogenesis
por: Yang, Feng, et al.
Publicado: (2014)

A systematic review and meta-analysis on the efficacy of stem cell therapy on bone brittleness in mouse models of osteogenesis imperfecta
por: Battle, Lauren, et al.
Publicado: (2021)

Bioinspired sandwich-like hybrid surface functionalized scaffold capable of regulating osteogenesis, angiogenesis, and osteoclastogenesis for robust bone regeneration
por: Wu, Minhao, et al.
Publicado: (2022)

CXCL chemokines-mediated communication between macrophages and BMSCs on titanium surface promotes osteogenesis via the actin cytoskeleton pathway
por: Zhang, Yayun, et al.
Publicado: (2023)

Nacre-inspired magnetically oriented micro-cellulose fibres/nano-hydroxyapatite/chitosan layered scaffold enhances pro-osteogenesis and angiogenesis
por: Ge, Yu-Wei, et al.
Publicado: (2022)

Preparation of co-electrospinning membrane loaded with simvastatin and substance P to accelerate bone regeneration by promoting cell homing, angiogenesis and osteogenesis
por: Al-Baadani, Mohammed A., et al.
Publicado: (2023)

A 3D bioprinted nano-laponite hydrogel construct promotes osteogenesis by activating PI3K/AKT signaling pathway
por: Miao, Sheng, et al.
Publicado: (2022)

SERPINF1 gene variants causing late-onset progressive deforming osteogenesis imperfecta – A study of 18 patients from India
por: Selina, Agnes, et al.
Publicado: (2023)

Amino acid metabolism in skeletal cells
por: Devignes, Claire-Sophie, et al.
Publicado: (2022)

The First Report of Differences in Gut Microbiota Composition between Obese and Normal Weight Iranian Subjects
por: Ettehad Marvasti, Fateme, et al.
Publicado: (2020)

Non-viral CRISPR activation system targeting VEGF-A and TGF-β1 for enhanced osteogenesis of pre-osteoblasts implanted with dual-crosslinked hydrogel
por: Chen, Guo, et al.
Publicado: (2022)

Puerarin promotes osteogenesis and inhibits adipogenesis in vitro
por: Wang, Nan, et al.
Publicado: (2013)

Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia
por: Pradillo, Jesus M., et al.
Publicado: (2017)

Interleukin 8 in postoperative delirium – Preliminary findings from two studies
por: Lammers-Lietz, Florian, et al.
Publicado: (2022)

Food phytochemicals, epigallocatechin gallate and myricetin, covalently bind to the active site of the coronavirus main protease in vitro
por: Kato, Yoji, et al.
Publicado: (2021)

A competition smFRET assay to study ligand‐induced conformational changes of the dengue virus protease
por: Maus, Hannah, et al.
Publicado: (2023)

FLNA-filaminopathy skeletal phenotypes are not due to an osteoblast autonomous loss-of-function
por: Wade, Emma M., et al.
Publicado: (2023)

Sex-specific associations between plasma interleukin-6 and depression in persons with and without HIV
por: Petersen, Kalen J., et al.
Publicado: (2023)

Association of a New Germline Variant in the MUTYH DNA Glycosylase Gene with Colorectal Adenoma Transformation into Malignancy
por: Mahasneh, Amjad, et al.
Publicado: (2019)

Therapeutic impact of low amplitude high frequency whole body vibrations on the osteogenesis imperfecta mouse bone()
por: Vanleene, Maximilien, et al.
Publicado: (2013)

Thiazide use and skeletal microstructure: Results from a multi-ethnic study
por: Huynh, Hoang-Long, et al.
Publicado: (2022)

Discovery of SARS-CoV-2 main protease covalent inhibitors from a DNA-encoded library selection
por: Ge, Rui, et al.
Publicado: (2022)

Differential redox potential profiles during adipogenesis and osteogenesis
por: Imhoff, Barry R., et al.
Publicado: (2010)

Interleukin 15 modulates the effects of poly I:C maternal immune activation on offspring behaviour
por: Haddad, Faraj L., et al.
Publicado: (2022)

Molecular interactions of STAC proteins with skeletal muscle dihydropyridine receptor and excitation‐contraction coupling
por: Shishmarev, Dmitry, et al.
Publicado: (2022)

Ultra-structural defects cause low bone matrix stiffness despite high mineralization in osteogenesis imperfecta mice()
por: Vanleene, Maximilien, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qt8vmbs6ra5rs1fkgem13ifgka