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Mammalian circular RNAs result largely from splicing errors

Ubiquitous in eukaryotes, circular RNAs (circRNAs) comprise a large class of mostly non-coding RNAs produced by back-splicing. Although some circRNAs have demonstrated biochemical activities, whether most circRNAs are functional is unknown. Here, we test the hypothesis that circRNA production primar...

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Detalles Bibliográficos
Autores principales: Xu, Chuan, Zhang, Jianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365531/
https://www.ncbi.nlm.nih.gov/pubmed/34320353
http://dx.doi.org/10.1016/j.celrep.2021.109439