An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration

BACKGROUND: The plasticity of monocytes enables them to exert multiple roles during an immune response, including promoting immune tolerance. How monocytes alter their functions to convey immune tolerance in the context of lower respiratory tract infections in humans is not well understood. Here, we...

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Detalles Bibliográficos
Autores principales: Brands, Xanthe, Haak, Bastiaan W., Klarenbeek, Augustijn M., Butler, Joe, Uhel, Fabrice, Qin, Wanhai, Otto, Natasja A., Jakobs, Marja E., Faber, Daniël R., Lutter, René, Wiersinga, W. Joost, van der Poll, Tom, Scicluna, Brendon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365568/
https://www.ncbi.nlm.nih.gov/pubmed/34399830
http://dx.doi.org/10.1186/s13073-021-00948-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365568/
https://www.ncbi.nlm.nih.gov/pubmed/34399830
http://dx.doi.org/10.1186/s13073-021-00948-1

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